Ultra-smooth, flow-optimized blood contact surfaces with CARMEDA ® BioActive Surface* coating for the best possible blood compatibility Safe de-airing through de-airing port Blood pumps with tri-leaflet valves made of polyurethane and blood pumps with bileaflet valves made of carbon

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Overview. The bioactive coating marketed by Medtronic under the name Cortiva BioActive Surface is the most researched biosurface for today's extracorporeal circulation technologies, with extensive publication of clinical and scientific evidence in peer-reviewed cardiovascular surgery, perfusion, and scientific literature.

Begovac PC, Thomson RC, Fisher JL, et al. Improvements in GoreTex vascular graft performance by Carmeda bioactive surface heparin immobilization. Eur J Vasc Endovasc Surg. 2003;25:432-437.

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J Thorac Cardiovasc Surg . (1996) 111:1073–84. doi: 10.1016/S0022-5223(96)70384-7 Begovac PC, Thomson RC, Fisher JL, Hughson A, Gällhagen A. Improvements in GORE-TEX® Vascular Graft performance by Carmeda® BioActive Surface heparin immobilization. European Journal of Vascular & Endovascular Surgery 2003;25(5):432-437. Lindholt JS, Gottschalksen B, Johannesen N, et al.

The CBAS Heparin Surface stays on the surface and remains bioactive on the EXCOR pump at least up until 1 year. This is an important demonstration of coating durability and supports the mid-term and long-term clinical use as bridge-to-heart transplantation or to myocardial recovery.

The facility includes ISO class 7 clean rooms and carefully controlled water and air supplies. This enables coating of Class III products according to both European and US requirements.

Because of its extensive publication history, there is emphasis on the CARMEDA ® BioActive Surface (CBAS ® Heparin Surface), a widely used commercialized technology for the covalent bonding of heparin.

(1996) 111:1073–84. doi: 10.1016/S0022-5223(96)70384-7 Ultra-smooth, flow-optimized blood contact surfaces with CARMEDA ® BioActive Surface* coating for the best possible blood compatibility Safe de-airing through de-airing port Blood pumps with tri-leaflet valves made of polyurethane and blood pumps with bileaflet valves made of carbon 2013-12-05 · The luminal surface of the GORE® VIABAHN® Endoprosthesis with Heparin Bioactive is modified with a covalently bound, bioactive heparin technology referred to as the Carmeda BioActive Surface (CBAS®). Figure 1: The GORE® VIABAHN® Endoprosthesis .

Författare. Clinical Durability of the CARMEDA BioActive Surface in EXCOR Ventricular Assist Device Pumps. Kalervo Werkkala, Janne J. Jokinen , Leena Soininen, Goran  1.0 Carmeda_chap.fm 9/10/07 12:57 pm CS0031 Produkt med Carmeda® BioActive Surface* Beskrivning Produktens blodkontaktytor är belagda med en  erkända företagen inom branschen för blodkompatibla ytbeläggningar, de har bland annat utvecklat produkten Carmeda® BioActive Surface  heparin coating: Carmeda Bioactive Surface, Baxter Duraflo II and a control group. Outcome was determined from a number of clinically oriented parameters,  B. The lumen of the GORE® ACUSEAL Vascular Graft is coated with the CARMEDA® BioActive Surface (CBAS® Surface) consisting of a stable,. covalently  Ytan som är i kontakt med blod är täckt med Carmeda® Bioactive Surface (CBAS TM)för att minska trombrisken. Eftersom pumpen är transparent är det enkel att  Improvements in GORE-TEX R Vascular Graft performance by Carmeda R BioActive Surface heparin immobilization Article in European Journal of Vascular and  Se Lovisa Odéns profil på LinkedIn, världens största yrkesnätverk. Lovisa har angett 11 jobb i sin profil.
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• Durable, non-leaching End Point. Attached  Nov 29, 2017 A bioactive heparin-bonded ePTFE graft utilizing.

(1996) 111:1073–84. doi: 10.1016/S0022-5223(96)70384-7 Begovac PC, Thomson RC, Fisher JL, Hughson A, Gällhagen A. Improvements in GORE-TEX® Vascular Graft performance by Carmeda® BioActive Surface heparin immobilization. European Journal of Vascular & Endovascular Surgery 2003;25(5):432-437.
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Carmeda bioactive surface





The CARMEDA® BioActive Surface is licensed to major medical device companies worldwide. Below is a selection of currently approved products featuring

Below is a selection of currently approved products featuring the  Clinical Durability of the CARMEDA BioActive Surface in EXCOR Ventricular Assist Device Pumps. Artikel i vetenskaplig tidskrift, refereegranskad.


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The CARMEDA ® BioActive Surface is a clinically proven and lasting thromboresistant heparin coating that actively prevents platelet adhesion and thrombus formation on medical device surfaces. The following features and benefits of the CARMEDA ® BioActive Surface have been shown in published clinical studies

Clinical Durability of the CARMEDA BioActive Surface in EXCOR Ventricular Assist Device Pumps.

The CARMEDA ® BioActive Surface is a clinically proven and lasting thromboresistant heparin coating that actively prevents platelet adhesion and thrombus formation on medical device surfaces. The following features and benefits of the CARMEDA ® BioActive Surface have been shown in published clinical studies

doi: 10.1097/MAT.0000000000000314. Authors 2003-05-01 16. Begovac PC, Thomson RC, Fisher JL, Hughson A, Gällhagen A. Improvements in GORE-TEX vascular graft performance by Carmeda BioActive surface heparin immobilization. Eur J Vasc Endovasc Surg.

The CARMEDA ® BioActive Surface is a clinically proven and lasting thromboresistant heparin coating that actively prevents platelet adhesion and thrombus formation on medical device surfaces. The following features and benefits of the CARMEDA ® BioActive Surface have been shown in published clinical studies 1996-05-01 · In the following experiments, we evaluated the heparin-bonded Carmeda Bioactive Surface (Medtronics Cardiopulmonary, Anaheim, Calif.) in an in vitro model of extracorporeal circulation at standard-dose heparin (5 U/ml), to examine the effects of the surface treatment on activation of blood elements, and at reduced-dose heparin (1 U/ml), to determine whether surface-bound heparin would serve as heparin, using the proprietary Carmeda BioActive Surface technology, and are referred to as CBAS-ePTFE grafts. This CBAS heparin immobilization produces a surface microstructure having stable, cova-lently bound heparin. The covalent end-point linkages maintain the catalytic bioactivity of the antithrombin (AT) sites of the bound heparin.13 The general principle of the CARMEDA ® BioActive Surface technology is to attach functionally active heparin to the blood contacting surfaces of medical devices.